故事发生在十九世纪的朝鲜，欧美东花岛上发生了装贡品的船被大火烧于一旦的案件，欧美为了调查案件的真相，朝廷派出了调查官李元奎（车胜元 饰）前往东花岛。哪知道一行人刚到岛上没多久，此地就发生了杀人事件，死者死相极为惨烈，让人不忍直视。很快，凶手便被捉拿归案，可之后，包括被捉拿的凶手在内，死者人数在不断的增加，这也就意味着，案件的黑手依然在幕后活动着，不仅如此，有关七年前枉死的安专员的灵魂作祟的消息不胫而走，而如今遇害的人们，都是和当年事件有着千丝万缕关联的存在。李元奎和画师斗浩（池城 饰）联手查案，却苦于毫无头绪。
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回复 :女主 康子由从美国毕业归国，多年辛苦工作后投入闺蜜 林千语 开办的医美中心做销售行政主任。她干练能干，年年提升公司业绩，在生活中却是一个邋遢大王生活白痴，全靠与前夫生下的女儿 康妮 照顾。女儿康妮是由姥姥一手培养出的家务小能手，自我又对烹饪，餐桌摆设有深厚的兴趣因此给妈妈带来了无比多样的美食生活。在遇到学长后，女儿不得已数次被需要照顾的妈妈打断约会，她渴望自己的生活，却难以舍弃妈妈。平静却有趣的生活中突然激起了一波涟漪，中心来了一个新的医美医师聂允泽。自此，邋遢的康子由与洁癖大王聂允泽处处冲撞，却也愈加亲密。与此同时，林千语的夫妻问题让康子由迫不得已与前夫老婆孟雨珊一起解决林千语的家庭阻碍，帮助闺蜜找到自我价值，摆脱不良老公。
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回复 :在上集幸存下来的人被神秘的先知Shot Bus Gus所救，他似乎拥有控制这些畜生的能力，在先知的带领下，幸存者进入下水道，那可通往城市，路上他们得到了空手道专家Jean-Claude Seagal的帮助，并得知这些畜生源自一个叫"The Hive."的地方，于是他们决定发起反击，永远消灭掉这些畜生。
